Endocrine Abstracts

A 21 years old male, diagnosed with ALL in 2003 (aged 9), completed treatment in June 2009 (aged 15). Chemotherapeutic agents included doxorubicin, daunorubicin, cytarabine, mercaptopurine, methotrexate, asparaginase, vincristine, dexamethasone (7 mg for 3.5 years). He didn’t receive any cranial irradiation. He underwent endocrine assessment aged 15 because of delayed puberty and had testosterone replacement for 4 years (September 2012 till January 2016). He also had hist...

Objective: To review impact of childhood cancer treatment on endocrine, gonadal and thyroid function.Methods: Retrospective review of electronic records of 79 females, 90 males over 6 months of clinic visits from a Late Effects of childhood cancer clinic. Age at diagnosis: 8.5 years (range 5 months–9 years); time from treatment 23.5 years (range 10–40). Diagnoses: ALL, AML, Hodgkin’s lymphoma, Non-Hodgkin’s lymphoma, sarcomas, Wilms, ...